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Fig. 5 | Molecular Medicine

Fig. 5

From: Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retina

Fig. 5

Insufficient Cav-1 levels alter the expression of VEGFR2 and VE-Cadherin in the retina. Expression of VEGFR2 and VE-Cadherin in 8-month-old Cav-1+/+ and Cav-1+/− retinas (A–C) was assessed by immunoblotting (A–C). Additionally, VEGFR2 protein content was assessed in Müller cells isolated from Cav-1+/+ and Cav-1+/− mouse retinas at p8-10 (D and E). γ-tubulin served as a loading control. Representative images (A and D) and quantifications obtained by pixel density assessments are shown (B, C and E). n = 4–6. *p < 0.05

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