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Fig. 2 | Molecular Medicine

Fig. 2

From: USP38 exacerbates atrial inflammation, fibrosis, and susceptibility to atrial fibrillation after myocardial infarction in mice

Fig. 2

Effect of USP38 cardiac-specific knockout on atrial inflammation after MI. (A) Representative immunohistochemical staining images. Left atria 3 days after MI were stained with anti-iNOS and CD163 antibody, respectively. (B-C) Quantitative analysis of the area of infiltrated iNOS positive and CD163 positive macrophages in the left atrial (n = 4). (D-E) mRNA expression of iNOS, and CD163 in the left atrial (n = 3). (F-H) mRNA expression levels of IL-1β, IL-6, and IL -10 (n = 4). (I-K) Levels of IL-1β, IL-6, and IL-10 proteins measured by ELISA (n = 5). *P < 0.05 vs. Sham group, #P < 0.05 vs. Flox-MI

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Molecular Medicine

ISSN: 1528-3658