Fig. 2
From: Loss of Krüppel-like factor-10 facilitates the development of chemical-induced liver cancer in mice
Liver fibrosis induction and gene expression in high-fat diet (HFD)-treated liver of KLF10 wild-type (WT) and knockout (KO) mice. A Liver tissue was stained for collagen deposition using Sirius red staining, and a morphometric analysis was performed. B The expression of Colα1 was evaluated by real-time polymerase chain reaction in WT mice fed a standard diet (SD) (n = 6), KLF10 KO mice fed an SD (n = 5), WT mice fed an HFD (n = 6), and KLF10 KO mice fed an HFD (n = 5). C Expression of TGFβ-related signaling genes. D Expression of αSMA. *P < 0.005 compared with SD-fed WT or KO mice