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Fig. 4 | Molecular Medicine

Fig. 4

From: Loss of Krüppel-like factor-10 facilitates the development of chemical-induced liver cancer in mice

Fig. 4

Gene expression in tumor sites of diethylnitrosamine (DEN)-treated liver of KLF10 wild-type (WT) and knockout (KO) liver. A The expression of TGFβ-related signaling genes was measured in WT mice without treatment (n = 8), KO mice without treatment (n = 8), WT mice with DEN treatment (n = 8), and KO mice with DEN treatment (n = 9). B The expression of epithelial-to-mesenchymal transition–related markers was evaluated. C The expression of genes related to tumor invasiveness was assessed. *P < 0.005 compared with SD-fed WT or KO mice

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