Fig. 5

Glab Alleviates the Autoinflammatory Response in Trex1^−/− Mice. A Representative images of various tissues stained with hematoxylin–eosin (H&E) staining (n = 6 mice per group). B–G WT mice (n = 6 per group) or Trex1^−/− Mice (n = 6 per group) were injected intraperitoneally with 40 mg/kg Glab or vehicle every other day for 14 consecutive days to incorporate the syndrome. Then, heart (B), muscle (C), tongue (D), stomach (E), kidney (F) and Intestines (G) tissues were collected and analyzed the mRNA expression of the indicated genes was determined by qPCR assay. Data in (B-G) are expressed as mean ± SEM (n = 6 mice per group). one-way ANOVA and Dunnett’s post hoc test were used to assess differences among groups, ^*p < 0.05, ^**p < 0.01 and ^***p < 0.001 vs. the control, NS, not significant