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Fig. 3 | Molecular Medicine

Fig. 3

From: FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6

Fig. 3

FGF21 administration protects the BBB in vivo after ICH. A, B Representative images and statistics analysis of Evans blue stain for each group 72 h after ICH. Red dot area: Evans blue volume. n = 6 per group. C, D Western blots and statistics analysis for ZO-1 and Occludin 72 h after ICH in vivo. n = 6 per group. *P < 0.05 indicates ICH + Vehicle vs ICH + FGF21 by student’s t test (B), **P < 0.01 vs Sham group and &P < 0.05 vs ICH + Vehicle group by two-way ANOVA (D). Values are presented as mean \(\pm\) SD

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Molecular Medicine

ISSN: 1528-3658