Fig. 7

FGF21 fails to protect neurofunction and the BBB in eSIRT6^−/− mice after ICH. A, B Representative images of TUNEL stain for SIRT6^flox/flox and eSIRT6^−/− mice 72 h after ICH. n = 6 per group. C, D Evans stain and Brain water content test for SIRT6^flox/flox and eSIRT6^−/− mice 72 h after ICH. n = 6 per group. E–G Sensorimotor tests for SIRT6^flox/flox and eSIRT6^−/− mice 72 h after ICH. n = 12 per group. Scale bar: 50 um. ^**P < 0.01, ^***P < 0.001 vs Sham group and ^&P < 0.05, ^&$P < 0.01 vs ICH + Vehicle group by two-way ANOVA B–G. ns: no significant. Values are presented as mean \(\pm\) SD