Fig. 1
From: Maresin1 ameliorates MSU crystal-induced inflammation by upregulating Prdx5 expression
MaR1 inhibited nuclear localization of p-P65 and expression of inflammation-associated genes. A BMDMs were treated with or without MaR1 (10 nM) for 1 h, then stimulated with FAs + MSUc for 12 h. Western blot detection of p-P65 and P65 protein levels in the nucleus and cytoplasm. B Quantitative PCR for mRNA levels of IL-1β, IL-6, TNF-α, iNOS, COX-2 and MCP1. C Western blotting detection of INOS and COX-2 protein levels. D Quantitative PCR and Western blot to detect P62 protein level. *Compared with no FAs + MSUc treatment, # compared with FAs + MSUc treatment. * and # means P < 0.05