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Fig. 1 | Molecular Medicine

Fig. 1

From: Cyclosporine A alleviates colitis by inhibiting the formation of neutrophil extracellular traps via the regulating pentose phosphate pathway

Fig. 1

NETs enrichment in UC patients. A Volcano plot of differential gene expression labeled with NETs gene-set in rectum between UC patients and HC. B Volcano plot of differential gene expression labeled with NETs gene-set in colon between UC patients and HC. C Volcano plot of differential gene expression labeled with NETs gene-set in whole blood between UC patients and HC. D NETs score in rectum of patients evaluated by histologic severity score (*P < 0.05 for patients with grade I/II vs grade III, **P < 0.01 for HC vs patients with grade III, **P < 0.01 for patients with grade I/II vs grade IV/V, ****P < 0.0001 for HC vs patients with grade IV/V). E NETs score in rectum of patients evaluated by Mayo score. F NETs score in colon of patients evaluated by MES. G NETs score in whole blood of patients evaluated by MES

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Molecular Medicine

ISSN: 1528-3658