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Fig. 3 | Molecular Medicine

Fig. 3

From: Cyclosporine A alleviates colitis by inhibiting the formation of neutrophil extracellular traps via the regulating pentose phosphate pathway

Fig. 3

Attenuated severity of colitis in DSS-induced mice model under the treatment of CsA. A Percentage of weight change in mice from day 1 to day 8 (**P < 0.01 for DSS vs DSS + CsA group, ****P < 0.0001 for Ctrl vs DSS group). B Disease activity index scores in mice from day 1 to day 8 (****P < 0.0001). C Appearance and lengths of colons in mice on day 8 (**P < 0.01, ****P < 0.0001). D Histological feature and scores of colons in mice on day 8. E The transcriptional level of TNF-α and IL-1β of colonic tissue in mice on day 8 (*P < 0.05, **P < 0.01)

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Molecular Medicine

ISSN: 1528-3658