Fig. 7
From: PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease
Schematic diagram of the underlying mechanism of PRMT3 on promoting the CKD-induced vascular calcification progression
CKD: chronic kidney disease; HIF-1α: hypoxia inducible factor 1 subunit alpha; LDHA: lactate dehydrogenase A; PFKFB3: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; PKM2: pyruvate kinase M1/2; PRMT3: protein arginine methyltransferase 3; VSMCs: vascular smooth muscle cells