Fig. 7
From: TIM-3 regulates the proliferation by BDNF-mediated PI3K/AKT axis in the process of endometriosis
LY294002 downregulated the activity of TIM-3 through the PI3K/AKT signaling pathway in vivo. (A, B) LY294002 inhibits the proliferation of ESCs and endometriotic nodules in vivo. (C, D) LY294002 inhibits the growth of endometriotic nodules in vivo. (E) LY294002 inhibits the expression of proliferation-related molecules through Western blotting. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)