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Fig. 8 | Molecular Medicine

Fig. 8

From: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts

Fig. 8

LND fibroblasts under physiological conditions show reduced migratory capacity. Migratory capacity was determined by scratch assay, as described in Material and methods, in control and LND fibroblasts cultivated with Plasmax-PV containing different levels of FA. A Images of the cell culture taken at 0, 5 and 10 h after the scratch was done. B Results were expressed in μm as the distance healed at each specific time point (5 and 10 h post-scratch). The results are the mean ± SEM of 3 controls and 3 LND patients taking 6 independent positions for each condition. *P < 0.05. Two-way ANOVA, Fisher’s multiple comparison test

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Molecular Medicine

ISSN: 1528-3658