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Fig. 4 | Molecular Medicine

Fig. 4

From: Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression

Fig. 4

KDM5C/PFDN5 regulates autophagic flux in CRC cells. A immunofluorescence staining to examine the LC-3B expression in the CRC cells (two-way ANOVA); B WB analysis to analyze the protein levels of ATG7, Beclin1, P62, and LC3-II/LC3-I (two-way ANOVA); C flow cytometry to analyze the apoptosis of CRC cells (two-way ANOVA). Three biological replicates were performed. *p < 0.05 vs. the sh-NC group; #p < 0.05 vs. the sh-KDM5C group

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Molecular Medicine

ISSN: 1528-3658