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Fig. 5 | Molecular Medicine

Fig. 5

From: Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression

Fig. 5

KDM5C/PFDN5 affects tumorigenesis of CRC cells in vivo. A representative images of xenograft tumors formed by HCT116 and SW480 cells on day 28 and the volume change of tumors during this period (two-way ANOVA); B weight of the xenograft tumors on day 28 (two-way ANOVA); C, activation of caspase-3 (cleaved-caspase-3) in tumor tissues examined by IHC. In each group, n = 5. *p < 0.05 vs. the sh-NC group; #p < 0.05 vs. the sh-KDM5C group

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