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Fig. 6 | Molecular Medicine

Fig. 6

From: Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression

Fig. 6

KDM5C/PFDN5 affects EMT in CRC. A protein levels of Vimentin and N-cadherin in HCT116 and SW480 cells determined by WB analysis (two-way ANOVA); B protein levels of Vimentin and N-cadherin in xenograft tumors determined by western blot analysis (two-way ANOVA). For cellular experiments, three biological replicates were performed. For animal studies, n = 5 in each group. *p < 0.05 vs. the sh-NC group; #p < 0.05 vs. the sh-KDM5C group

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