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Table 1 Correlations between KDM5C and PFDN5 expression and clinicopathologic features in patients with CRC

From: Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression

Features

KDM5C expression

p value

PFDN5 expression

p value

High (n = 34)

Low (n = 38)

High (n = 33)

Low (n = 39)

Age (years)

      

  < 65

17

21

0.8134

21

17

0.1032

  ≥ 65

17

17

 

12

22

 

Sex

      

 Male

20

19

0.4861

15

24

0.2359

 Female

14

19

 

18

15

 

TNM stage

      

 T1-2

1

12

0.0017

12

1

0.0003

 T3-4

33

26

 

21

38

 

LNM

      

 Absent

11

26

0.0043

23

14

0.0051

 Present

23

12

 

10

25

 
  1. The clinical data were analyzed using Fisher's exact test. A p value less than 0.05 was indicative of statistical significance. KDM5C lysine demethylase 5C, PFDN5 prefoldin subunit 5, CRC colorectal cancer, TNM tumor node metastasis, LNM lymph node metastasis
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Molecular Medicine

ISSN: 1528-3658