Fig. 3
From: Small noncoding RNAs and sperm nuclear basic proteins reflect the environmental impact on germ cells
DE miRNA characterization with respect to subject parameters and publicly available miRNA expression profiles. A Heatmap of Spearman’s correlation coefficients (Rho) computed between the 32 DE miRNAs levels and the spermiogram parameters, SNBP properties, and trace metals parameters (*p < 0.05). B Scatter plots showing the correlations between sperm concentration and miR-23a-3p, miR-3135a-3p, let-7f-5p, and miR-23b-3p expression levels. C Bar plot of the normalized expression of the subset of 32 DE miRNAs detected in two publicly available miRNA expression profiles datasets of human semen: GSE40181, (blue) and GSE159155 (red). D Comparison between miRNA levels during differentiation of mice germ cells (data from GSE36566): reported miRNAs are the mice homologous of the identified human DE miRNAs in the present study. The log2FCs were computed with respect to miRNA levels in mice gonocytes. The dot color represents miRNA log2FC, while the size is proportional to the p-value of the analysis