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Fig. 6 | Molecular Medicine

Fig. 6

From: Decellularized nucleus pulposus matrix/chitosan hybrid hydrogel combined with nucleus pulposus stem cells and GDF5-loaded microspheres for intervertebral disc degeneration prevention

Fig. 6

The composite hydrogels with GDF5-loaded microspheres loaded with NPSCs had the best repair effect on IDD. (A) Description of animal experiment. (B–C) Observation of rat tail intervertebral disc degeneration in each group by MRI and classification analysis. (D–E) Observation of rat tail intervertebral disc in each group by safranine and fast green staining and classification analysis. (F–G) The COL2A1 expression level in NP tissues in the six groups were determined by immunohistochemistry and quantitative analysis. (n ≥ 3, *p < 0.05, **p < 0.01)

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Molecular Medicine

ISSN: 1528-3658