Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis

Fig. 5

MT enhanced the antioxidant capacity of BMMs from aged mice. A DCFH fluorensence analyses of intracellular ROS level in BMMs from young mice, old mice and old mice with MT treatment. Data represent mean ± S.D. of at least three independent experiments (n = 3 per group). B Representative fluorescence images of Nrf2 expression. C–F Western blot analysis of protein levels of Nrf2, Keap1 and HO-1. *p < 0.05, **p < 0.01, ****p < 0.0001 compared with the young group; #p < 0.05, ##p < 0.01, ####p < 0.0001 compared with the old group

Back to article page