Fig. 7From: Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasisMT supplementation alleviated the deterioration of bone microstructure and bone loss in aged mice. A Representative micro-CT images of the distal femur from old mice, old mice with vehicle and old mice with MT treatment. B–H Quantitative parameters in the distal femur, including bone mineral density (BMD), bone volume fraction (BV/TV), trabecular thickness (Tb/Vt.Th), trabecular number (Tb/Vt.N), trabecular separation (Tb/Vt.Sp), cortical bone thickness (Ct.th) and average cortical bone area (Ct.BArea). I Representative μCT images of L4 vertebral bodies. J–N Quantitative parameters in L4 vertebral bodies. Data represent mean ± S.D. of at least three independent experiments (n = 6 per group). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, not significantBack to article page