Fig. 7

NAT10 expression positively correlates with PD-L1 expression and is associated with poor prognosis. A Representative images of IHC staining of NAT10 (left) and PD-L1 (right) in colon cancer tissues. B H-scores of NAT10 staining in human colon cancer tissues and normal adjacent tissues. Data are presented as the mean ± s.d. **P < 0.01. C Kaplan‒Meier analysis based on NAT10 expression in colon cancer patients. Data were analyzed by the two-sided log rank test, P = 0.041. D Kaplan‒Meier analysis based on NAT10 expression in TNBC patients using the Kaplan‒Meier Plotter database. E Correlation analysis between NAT10 expression and PD-L1 expression in 40 TNBC patients. Two-tailed Pearson’s chi-square test was used to determine the correlation. F The correlation between NAT10 and PD-L1 (CD274) expression levels in breast cancer and lung adenocarcinoma in the TIMER 2.0 database