Fig. 5
From: Comprehensive analysis of m6A modification in lipopolysaccharide-induced acute lung injury in mice
Conjoint analysis of m6A methylation and mRNA expression. (A) Four-quadrant plot showed the genes with both differential m6A peaks and concordant mRNA expression changes. (B) GO terms for the overlapped genes. (C) Enriched pathways for the overlapped genes. (D) PPI network analysis for the overlapped genes. (E, F) Relative mRNA levels of eleven hub genes and western blots for Flrt3, PKG, CaMKII and p-CaMKII in lung tissues and quantitative outcomes (n = 6). (G-N) Relative mRNA levels of eleven hub genes and western blots for Flrt3, PKG, CaMKII and p-CaMKII respectively in differentiated THP-1 cells, HPMECs, HUVECs and A549 cells, and corresponding quantitative outcomes (n = 6). (Values are presented as Mean ± SD, *p < 0.05)