Skip to main content
Fig. 1 | Molecular Medicine

Fig. 1

From: α-Ketoglutarate improves cardiac insufficiency through NAD+-SIRT1 signaling-mediated mitophagy and ferroptosis in pressure overload-induced mice

Fig. 1

AKG improves cardiac dysfunction in TAC mice. (A) The timeline of vivo experiments. (B) Echocardiogram of each group at 8 weeks after surgery. (C) Statistical analysis of left ventricular posterior wall thickness at diastole (LVPWd), left ventricular posterior wall thickness at systole (LVPWs), left ventricular internal diameter at diastole (LVIDd), left ventricular internal diameter at systole (LVIDs), left ventricular ejection fraction (LVEF), and left ventricular shortening fraction (LVFS). *P < 0.05, **P < 0.01, ***P < 0.001 vs. Sham; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. TAC

Back to article page

Molecular Medicine

ISSN: 1528-3658