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Fig. 1 | Molecular Medicine

Fig. 1

From: Involvement of Fgf2-mediated tau protein phosphorylation in cognitive deficits induced by sevoflurane in aged rats

Fig. 1

Effects of sevoflurane exposure on rats’ learning, cognition, and motor ability. Note: (A) Behavioral Experiment Design and Timeline; (B–D) Line graphs showing the changes in escape latency during different days in the water maze experiment for rats in different treatment groups at 3 months (Fig. B), 12 months (Fig. C), and 18 months (Fig. D); (D–F) Bar graphs showing the time required for rats in different treatment groups at 3 months (Fig. E), 12 months (Fig. F), and 18 months (Fig. G) to find the target platform on different days in the water maze experiment; (H) Open field test measuring the time for 18-month-aged rats in different treatment groups to initiate movement; (I) Open field test measuring the total distance traveled by 18-month-aged rats in different treatment groups; (J) Index of novel object recognition in the open field test. P < 0.05, P < 0.01, **P < 0.001, all significances are compared between the Sevo and Control groups; each group consisted of 7 rats

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