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Fig. 2 | Molecular Medicine

Fig. 2

From: Porous Se@SiO2 nanospheres alleviate diabetic retinopathy by inhibiting excess lipid peroxidation and inflammation

Fig. 2

Porous Se@SiO2 nanospheres inhibit diabetes-induced retinal lipid peroxidation and inflammation. A Levels of MDA in retinal homogenates (n = 6). B Expression levels of GPX4 in retinas were measured using western blotting; β‐actin was used as a loading control (left panel). Band densities were assessed using the ImageJ software, and GPX4 expression levels are represented as their ratios to β‐actin (right panel) (n = 3). Levels of GSH (C), GSSG (D), and the ratio of GSH to GSSG (E) in retinal homogenates (n = 6). Protein expression levels of TNF-α (F), IFN-γ (G), and IL-1β (H) in retinal homogenates (n = 6). Relative mRNA expression levels of TNF-α (I), IFN-γ (J), and IL-1β (K) in retinal homogenates (n = 6). Data are represented as the mean ± SD. **p < 0.01, ***p < 0.001; ns, nonsignificant

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