Fig. 6
From: BATF and BATF3 deficiency alters CD8+ effector/exhausted T cells balance in skin transplantation
BATF and BATF3 deficiency led to long term inhibition of effector CD8 + T cells. A At day 100 post-BALB/c skin grafting, the adoptively transferred batf−/−batf3−/− and control CD8+ T cells in B6.Rag1−/− recipients were analysed. B Representative contour plots show percentage of the CD8+TCR-β+ cells in spleen and dLNs CD8+ cells. C Bar graphs show percentage a CD8+TCR-β+ cells in spleen and dLNs CD45+ cells and number of CD8+ TCR-β + cells in spleen and dLNs. D, E % of CD44+KLRG-1+ cells and TNF-α+IFN-γ+ cells in spleen CD8+ T cells. Data in C, E are shown as mean ± SD and are from one experiment that is representative of 2 independent experiments. ns, p > 0.05; *p < 0.05; **p < 0.01; ***p < 0.001 by unpaired Student’s t-test