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Table 2 Susceptibility of KP and CRKP strains to 10 antimicrobial drugs

From: Understanding blaNDM-1 gene regulation in CRKP infections: toward novel antimicrobial strategies for hospital-acquired pneumonia

Antibiotics

Drug content of paper /μg

Inhibitory ring diameter (mm)

R (mm)

I (mm)

S (mm)

KP (mm)

CRKP (mm)

Ertapenem

10

 ≤ 18

19–21

 ≥ 22

24.1 ± 1.5

10.0 ± 1.4*

Imipenem

10

 ≤ 19

20–22

 ≥ 23

26.2 ± 1.9

5.9 ± 1.1*

Meropenem

10

 ≤ 19

20–22

 ≥ 23

26.1 ± 2.4

11.5 ± 2.2*

Chloramphenicol

30

 ≤ 12

13–17

 ≥ 18

20.0 ± 1.5

5.9 ± 0.9*

Ciprofloxacin

5

 ≤ 21

22–25

 ≥ 26

29.9 ± 2.9

12.6 ± 1.9*

Levofloxacin

5

 ≤ 16

17–20

 ≥ 21

24.9 ± 2.0

5.0 ± 0.6*

Ceftazidime

30

 ≤ 17

18–20

 ≥ 21

26.0 ± 2.6

8.8 ± 1.3*

Ceftriaxone

30

 ≤ 19

20–22

 ≥ 23

28.1 ± 2.4

6.8 ± 1.1*

Cefoxitin

30

 ≤ 14

15–17

 ≥ 18

25.2 ± 2.0

5.8 ± 0.8*

Aztreonam

30

 ≤ 17

18–20

 ≥ 21

26.0 ± 2.2

9.1 ± 1.5*

  1. R Resistance, I Intermediary, S Sensitive. The measured data in the figure is presented as Mean ± SD, with 3 times in each group. *Represents a significant difference compared to the PBS group, *P < 0.05
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Molecular Medicine

ISSN: 1528-3658