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Table 3 MICs of KP and CRKP strains against 10 antimicrobial drugs

From: Understanding blaNDM-1 gene regulation in CRKP infections: toward novel antimicrobial strategies for hospital-acquired pneumonia

Antibiotics

MICs (μg/mL)

R (μg/mL)

I (μg/mL)

S (μg/mL)

KP (μg/mL)

CRKP (μg/mL)

Ertapenem

 ≥ 2

1

 ≤ 0.5

0.2 ± 0.1

18.5 ± 4.1*

Imipenem

 ≥ 4

2

 ≤ 1

0.8 ± 0.4

16.1 ± 3.3*

Meropenem

 ≥ 4

2

 ≤ 1

1.2 ± 0.7

20.0 ± 3.9*

Chloramphenicol

 ≥ 32

16

 ≤ 8

5.2 ± 0.9

31.8 ± 5.5*

Ciprofloxacin

 ≥ 1

0.5

 ≤ 0.25

0.2 ± 0.1

28.2 ± 3.1*

Levofloxacin

 ≥ 2

1

 ≤ 0.5

0.5 ± 0.2

30.1 ± 5.0*

Ceftazidime

 ≥ 16

8

 ≤ 14

8 ± 1.9

27.8 ± 2.3*

Ceftriaxone

 ≥ 4

2

 ≤ 1

1 ± 0.8

19.6 ± 1.9*

Cefoxitin

 ≥ 32

16

 ≤ 8

5 ± 0.8

32.2 ± 4.7*

Aztreonam

 ≥ 16

8

 ≤ 4

3 ± 0.8

26.0 ± 4.6*

  1. R Resistance, I Intermediary, S Sensitive. The measured data in the figure is presented as Mean ± SD, with 3 times in each group. *Represents a significant difference compared to the PBS group, *P < 0.05
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Molecular Medicine

ISSN: 1528-3658