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Fig. 3 | Molecular Medicine

Fig. 3

From: Artemisinin ameliorates cognitive decline by inhibiting hippocampal neuronal ferroptosis via Nrf2 activation in T2DM mice

Fig. 3

Artemisinin increases the protein levels of Nrf2, HO-1, and GPX4 in the hippocampal CA1. T2DM mice were treated with artemisinin (Art, 40 mg/kg/d, i.p.) for 4 consecutive weeks. A Western blot analysis was performed to measure the expression of p-Nrf2, Nrf2, HO-1, and GPX4. B–D The relative optical density values of Nrf2, HO-1 and GPX4 proteins were quantified by NIH ImageJ software. β-actin was used as a control for protein loading. fold of control: relative fold change compared to the control group. The data are expressed as the mean ± SEM (n = 4 per group). *P < 0.05, **P < 0.001

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Molecular Medicine

ISSN: 1528-3658