Fig. 5
WSB1 resulted in activation of β-catenin signaling in myocardial cells. A The levels of Wnt1, total β-catenin, non phosphor (active) β-catenin and nuclear β-catenin in myocardial cells. B The total GSK3β, p-GSK3βS9 and p-GSK3β.Y216 levels in myocardial cells after OGD/R administration and WSB1 overexpression/silencing. C The distribution of β-catenin in myocardial cells was indicated with immunofluorescence staining (the scale bar represented as 50 μm). D The mRNA levels of c-MYC and cyclin D1. (OGD, oxygen-sugar deprivation; WSB1, WD repeat and SOCS box containing 1; GSK3β, glycogen synthase kinase 3 beta; **p < 0.01, ***p < 0.001)