Fig. 3
From: Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
HTT1a is generated in a CAG repeat-length-dependent manner in post mortem brain regions
HTT1a normalised to HTT exon 2 (HTTex2) expression levels in sensorimotor cortex (A), motor cortex (BA4) (B), BA9 cortex (C) and cerebellum (D) were analysed from HTT mutation carriers with adult-onset CAG repeat lengths (HD) or juvenile-onset CAG repeat lengths (HD juvenile) and control individuals (control), respectively. The black line represents the linear model of expression level with CAG repeat length. R2 (coefficient of determination) and P value for the fit of the linear modelling are shown. Grey areas represent the standard error of the regression model. For data showing the individual HTT isoform expression levels see supplementary Figure S2.