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Fig. 5 | Molecular Medicine

Fig. 5

From: Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues

Fig. 5

HTT1a is generated in a CAG repeat-length-dependent manner in PBMCs, but not in skeletal muscle tissue

HTT1a and HTT exon 2 (HTTex2) expression in human skeletal muscle tissue (A) or PBMCs (B) was analysed from HTT mutation carriers (HD) or control individuals (control). The black line represents the linear model of expression level with CAG repeat length. R2 (coefficient of determination) and Pvalue for the fit of the linear modelling are shown. Grey areas represent the standard error of the regression model.

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