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Fig. 2 | Molecular Medicine

Fig. 2

From: Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer

Fig. 2

G-Rh2 inhibited tumor growth and promoted apoptosis in vivo. (A) Representative images of A549 tumor formation in the xenografts of nude mice. (B) Measurement of mouse weights after G-Rh2 treatment for 14 days. (C) Summary of tumor volumes recorded every 2 days. Data are expressed as mean ± SD. (D) Determination of tumor weights 14 days after intraperitoneal injection of G-Rh2.Data are expressed as mean ± SD. (E-H) Immunohistochemical analysis showing the percentages of Ki67-positive and TUNEL-positive cells. Data are expressed as mean ± SD. **P < 0.01, ***P < 0.001, ****P < 0.001 vs. the control group

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