Fig. 3

Effects of tLAP and SE-tLAP on the inflammation and fibrosis of TGF-β1-induced NIH-3T3 cells. (A-D). Detection of the mRNA expressions of TGF-β1, IL-6, α-SMA, and Col-I in NIH-3T3 cells. (E). Protein expressions of α-SMA and FN in NIH-3T3 cells. (F-G). Quantitative analysis of α-SMA and FN. (H). Detection of the Col-I expression in NIH-3T3 cells. ^###P < 0.001, ^####P < 0.0001 vs. Control; *P < 0.05,**P < 0.01, ***P < 0.001, ****P < 0.0001 vs. TGF-β1; ^ΔP < 0.05,^ΔΔΔP < 0.001, tLAP vs. SE-tLAP