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Fig. 6 | Molecular Medicine

Fig. 6

From: F127-SE-tLAP thermosensitive hydrogel alleviates bleomycin-induced skin fibrosis via TGF-β/Smad pathway

Fig. 6

6F127-SE-tLAP hydrogel alleviated bleomycin-induced skin fibrosis. (A). HE staining results of skin tissues (Magnifcation×100, scale bars = 100 μm). (B). Masson staining results of skin tissues (Magnifcation×100, scale bars = 100 μm). (C). Immunohistochemical staining of Col-I (magnifcation×400, scale bars = 50 μm). (D). Immunohistochemical staining of α-SMA (magnifcation×400, scale bars = 50 μm). (E). Analysis of the dermal thickness. (F). Quantitative analysis of Masson. (G). Immunohistochemical analysis of Col-I. (H). Immunohistochemical analysis of α-SMA. (I). Analysis of hydroxyproline content in skin tissues. ####P < 0.0001 vs. Control; **P < 0.01,***P < 0.001, ****P < 0.0001 vs. TGF-β1; ΔP < 0.05, ΔΔP < 0.01, ΔΔΔP < 0.001,F127-tLAP vs. F127-SE-tLAP

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