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Fig. 2 | Molecular Medicine

Fig. 2

From: CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway

Fig. 2

The expression of CHMP5 was decreased in OA human and mouse articular cartilages. (A) The protein content of CHMP5 was determined in normal and OA patient cartilages by western blot. (B) Safranin O-fast green staining images and OARSI score of articular cartilages from the sham and DMM mice at 8 weeks after surgery (Mann-Whitney test). Bar: 500 μm. (C) Real time PCR and (D) immunohistochemistry (IHC) showed the expression of CHMP5 in the mouse cartilages (Mann-Whitney test). Bar: 50 μm. **P < 0.01. ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658