Fig. 7From: CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathwayCHMP5 mitigated OA progression in the DMM-mediated mice. (A) CHMP5 diminished mouse cartilage destruction (Mann-Whitney test). Bar: 500 μm. (B-D) CHMP5, Collagen II, and MMP-13 were examined by IHC assay (Mann-Whitney test). Bar: 50 μm. *P < 0.05. **P < 0.01Back to article page