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Fig. 2 | Molecular Medicine

Fig. 2

From: Elk1 enhances inflammatory cell infiltration and exacerbates acute lung injury/acute respiratory distress syndrome by suppressing Fcgr2b transcription

Fig. 2

Th17 cell infiltration in ARDS rats is reduced by overexpressing Fcgr2b. Notes A, Immunohistochemistry to examine Fcgr2b expression in lung tissues of ARDS rats; B, immunohistochemistry to examine Fcgr2b expression in lung tissues of AAV-Fcgr2b-treated ARDS rats; C, immunohistochemistry to measure RORγt expression in lung tissues of each group of rats; D, Flow cytometry to determine the cell counts of Macrophage, Neutrophils, Lymphocytes and Th17 cells in BALF of each group of rats; E, ELISA to detect IL-17 and IL-6 expression in BALF of each group of rats. F, Photographs showing Evans blue accumulation in lung tissues (n = 6/group). Differences between two groups were compared using the t-test (A-B), and differences among multiple groups were compared using one-way or two-way analysis of variance with Tukey’s post-hoc test (C-E). AAV, adeno-associated virus; ARDS, acute respiratory distress syndrome; BALF, bronchoalveolar lavage fluid

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Molecular Medicine

ISSN: 1528-3658