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Fig. 7 | Molecular Medicine

Fig. 7

From: Elk1 enhances inflammatory cell infiltration and exacerbates acute lung injury/acute respiratory distress syndrome by suppressing Fcgr2b transcription

Fig. 7

Fcgr2b downregulation represses the protective effect of Elk1 knockdown on LPS-induced cell injury in PMVECs. Notes A, CCK-8 assay for cell activity of LPS-induced PMVECs; B, detection of LDH release in LPS-induced PMVECs; C, TUNEL assay for apoptosis of LPS-induced PMVECs; D, tubule formation assay for the angiogenic capacity of LPS-induced PMVECs; E, western blot for VE-cadherin and β-catenin protein expression in LPS-induced PMVECs. N = 3. Differences among multiple groups were compared using one-way (A-D) or two-way (E) analysis of variance with Tukey’s post-hoc test. LPS, lipopolysaccharide; PMVECs, pulmonary microvascular endothelial cells; LDH, lactate dehydrogenase

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Molecular Medicine

ISSN: 1528-3658