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Table 1 Metabolic parameters of fed and fasted WT and ICAM-1-deficient mice a

From: ICAM-1 and β2 Integrin Deficiency Impairs Fat Oxidation and Insulin Metabolism during Fasting

Metabolite measurements

Fed

Fasted

WT

ICAM-1-deficient

P

WT

ICAM-1-deficient

P

Triglycerides (mg/dL)

55.8 ± 5.1

38.7 ± 5.6

<0.05

29.5 ± 6.2

88 ± 8.7

<0.01

FFA (meq/L)

0.49 ± 0.04

0.63 ± 0.08

>0.05

0.86 ± 0.07

1.19 ± 0.09

<0.01

β-hydroxybutyrate (mg/dL)

0.7 ± 0.05

0.8 ± 0.08

>0.05

25.5 ± 1.6

8.8 ± 1.0

<0.01

Glycogen (mg/100 g of liver tissue)

4333 ± 135

4703 ± 459

>0.05

218.5 ± 49.7

37.92 ± 15.5

<0.01

  1. aFasting induces disturbance in serum concentration and liver content of several analytes in ICAM-1-deficient mice. WT or ICAM-1-deficient mice were bled at the end of the dark cycle (9 a.m.). Data were analyzed by unpaired t test followed by normality posttest. Each experimental group had 7 to 8 mice.