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Figure 6 | Molecular Medicine

Figure 6

From: Chemokine Receptor CCR1 Disruption in Bone Marrow Cells Enhances Atherosclerotic Lesion Development and Inflammation in Mice

Figure 6

Representative photomicrographs showing immunostaining for oxidized phospholipids recognized by a biotinylated EO6 antibody (a), for CD3 (T lymphocytes in b), and IFN-γ (c, d) in spleen sections from the two groups of mice at the time of death. Staining with EO6 and CD3 is shown for CCR1−/− mice and was highly similar to staining observed in CCR1+/+ mice. Areas showing accumulation positive EO6 staining also showed positive staining for IFN-γ. IFN-γ staining was much more pronounced in CCR1−/− (d) than in CCR1+/+ (c) mice.

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