Figure 1From: Real-Time PCR and Linkage Studies to Identify Carriers Presenting HPRT Deleted GeneFamily 1 pedigree and haplotype. Microsatellites and SNPs are listed in order of map position. II.3 is the proband, carrier of the deletion from exon 1 to 3 in HPRT gene. With the use of 3 microsatellite markers and 4 SNPs, the affected allele segregation can be followed; this affected allele is present only in the proband’s sister and mother.Back to article page