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Table 1 Inhibition of Maize HDAC by ITF2357

From: The Histone Deacetylase Inhibitor ITF2357 Reduces Production of Pro-Inflammatory Cytokines In Vitro and Systemic Inflammation In Vivo

Compound HD2 HD1-B HD1-A
ITF2357 10a 7.5 16
ITF2363b 1150 420 300
ITF2375c NA NA NA
  1. aInhibitory concentration of 50% in nM.
  2. bChemical name 4-aminobenzohydroxamic acid.
  3. cInactive metabolite of ITF2357.
  4. NA indicates no activity.