Table 1 Fold change of genes whose expression is increased by the combination of E2 + DIM

Cytochrome P450 CYP1B1

NM_000104

1.389 ± 0.12

3.101 ± 0.22

3.93 ± 0.25

Cytochrome P450, CYP1B1

NM_000104.2

1.436 ± 0.15

2.738 ± 0.26

3.32 ± 0.32

Cytochrome P450, CYP1B1

NM_000104.2

1.581 ± 0.13

2.617 ± 0.53

2.86 ± 0.66

Cytochrome P450 CYP1A1

NM_000499

0.773 ± 0.13

2.605 ± 0.61

2.84 ± 0.51

Stearoyl-CoA desaturase (delta-9-desaturase)

AF116616.1

1.533 ± 0.14

1.96 ± 0.34

2.40 ± 0.28

Caldesmon 1

NM_018495

1.708 ± 0.32

1.75 ± 0.33

2.37 ± 0.31

Solute carrier family 7/ member 11

AB040875.1

1.444 ± 0.17

1.566 ± 0.19

1.90 ± 0.13

p8 protein (candidate of metastasis 1)

AF135266.1

1.118 ± 0.12

1.395 ± 0.45

1.92 ± 0.27

Interferon-induced protein/ tetratricopeptide repeats 1

NM_001548

0.93 ± 0.17

1.438 ± 0.13

1.88 ± 0.20

Nucleophosmin/nucleoplasmin, 3

NM_006993

1.72 ± 0.22

1.775 ± 0.16

1.85 ± 0.16

Amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)

X06989.1

1.717 ± 0.39

1.624 ± 0.31

1.84 ± 0.32

Zinc finger protein 557

NM_024341

1.324 ± 0.12

1.559 ± 0.21

1.83 ± 0.20

Like Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial precursor

NM_025001

1.263 ± 0.13

1.055 ± 0.20

1.81 ± 0.23

Asparagine synthetase

NM_001673

1.267 ± 0.16

1.303 ± 0.32

1.81 ± 0.25

GTP bp overexpressed in skeletal muscle

NM_005261

1.666 ± 0.12

1.133 ±0.19

1.78 ± 0.21

TBC1 domain family, member 5

NM_014744

1.486 ± 0.11

1.395 ± 0.16

1.76 ± 0.12

Fatty acid binding protein 5 (psoriasis-assoc)

NM_001444

1.564 ± 0.12

1.33 ± 0.12

1.75 ± 0.12

Clathrin, heavy polypeptide (Hc)

NM_014127

1.406 ± 0.24

1.43 ± 0.29

1.75 ± 0.85

Solute carrier family 33 (acetyl-CoA transporter)1

NM_004733

1.338 ± 0.15

1.348 ± 0.13

1.69 ± 0.21

Hypothetical protein FLJ21148

NM_024860

1.469 ± 0.17

1.424 ± 0.17

1.68 ± 0.16

Thyroid receptor interacting protein 15

AA496247

1.088 ± 0.15

1.226 ± 0.13

1.68 ± 0.20

FK506 binding protein 14, 22 kDa

NM_017946

1.165 ± 0.15

1.247 ± 0.21

1.65 ± 0.16

Stromal antigen 2

BC001765.1

1.359 ± 0.43

1.553 ± 0.81

1.65 ± 1.29

Kelch-like 9 (Drosophila)

AW138594

1.495 ± 0.17

1.38 ± 0.13

1.64 ± 0.26

Phosphoglycerate dehydrogenase

NM_006623

1.167 ±0.10

1.399 ± 0.17

1.64 ± 0.13

Diacylglycerol kinase, epsilon 64kDa

NM_003647

1.119 ± 0.25

1.53 ± 0.16

1.62 ± 0.24

KIAA0746 protein

AB018289.1

1.227 ± 0.10

1.361 ± 0.19

1.62 ± 0.16

Aldo-keto reductase family 1, member C3

NM_003739

0.901 ± 0.13

1.309 ± 0.18

1.62 ± 0.13

Insulin induced gene 1

NM_005542

1.395 ± 0.11

1.41 ± 0.27

1.56 ± 0.14

Esterase D/formylglutathione hydrolase

AU145746

1.306 ± 0.15

1.078 ± 0.16

1.55 ± 0.15

Transducin (beta)-like 1X-linked receptor 1

NM_030921

1.42 ±0.15

1.341 ± 0.13

1.53 ± 0.14

Ataxin 1

AW235612

1.361 ± 0.36

1.361 ± 0.35

1.53 ± 0.24

Similar to 0610010D24Rik protein

AF070587.1

1.121 ± 0.12

1.337 ± 0.18

1.52 ± 0.12

Deleted in liver cancer 1

AF026219.1

1.361 ± 0.15

1.108 ± 0.12

1.50 ± 0.14