Table 2 Fold change of genes whose expression is diminished by the combination of E2 + DIM

Mitochondrial ribosomal protein L2

NM_015950

0.758 ± 0.09

1.035 ± 0.22

0.666 ± 0.10

Tumor protein p53 (Li-Fraumeni disease)

NM_000546

0.873 ± 0.11

0.889 ± 0.15

0.663 ± 0.10

HERV-H LTR-associating 3

NM_007071

0.942 ± 0.12

0.929 ± 0.16

0.662 ± 0.14

Lipin 2

U55968

0.983 ± 0.09

0.82 ± 0.16

0.659 ± 0.10

ATP-binding cassette, D (ALD), 1

NM_000033

0.894 ± 0.09

0.911 ± 0.13

0.653 ± 0.10

Cytoplasmic FMR1 interacting protein 2

NM_030778

0.903 ± 0.09

0.844 ± 0.17

0.653 ± 0.11

Endothelin converting enz 1

BF969352

0.858 ± 0.11

0.723 ± 0.19

0.648 ± 0.11

Aldehyde dehydrogenase 3 B1

BC002553.1

0.84 ± 0.09

0.718 ± 0.15

0.648 ± 0.12

ATP-binding cassette,G 1

U34919.1

0.754 ± 0.12

0.809 ± 0.14

0.648 ± 0.11

Kelch domain containing 3

BF063121

0.949 ± 0.16

1.11 ± 0.14

0.639 ± 0.11

Erythropoietin receptor

M34986.1

0.782 ± 0.09

0.788 ± 0.15

0.636 ± 0.12

Tripartite motif-containing 3

AA114843

0.764 ± 0.10

0.743 ± 0.15

0.633 ± 0.12

GPI-anchored metastasis-associated proteinhomolog

NM_014400

0.693 ± 0.09

0.88 ± 0.13

0.631 ± 0.10

DEAD box polypeptide 54

NM_024072

1.185 ± 0.17

0.863 ± 0.25

0.619 ± 0.18

Distal-less homeobox 4

NM_001934

0.777 ± 0.11

0.944 ± 0.15

0.618 ± 0.12

Slingshot homolog 3 (Drosophila)

NM_018276

0.861 ± 0.11

0.936 ± 0.13

0.617 ± 0.14

Synaptobrevin 2

BC002737.1

0.675 ± 0.10

1.09 ± 0.26

0.617 ± 0.12

Ribosomal protein S6 kinase, 90kDa, polypeptide 4

NM_003942

0.813 ± 0.12

0.912 ± 0.19

0.615 ± 0.10

Chromodomain helicase DNA binding protein 3

BE379542

0.751 ± 0.15

0.848 ± 0.12

0.615 ± 0.10

TGFB1-induced anti-apoptotic factor1

NM_004740

0.858 ± 0.09

0.915 ± 0.17

0.612 ± 0.12

Agrin

AK021586.1

0.849 ± 0.10

1.187 ± 0.18

0.607 ± 0.12

Kynurenine 3-monooxygenase

AI074145

0.744 ± 0.11

0.697 ± 0.13

0.601 ± 0.11

Chr 20 ORF 149

NM_024299

0.796 ± 0.14

1.169 ± 0.31

0.596 ± 0.11

SH3 domain binding glutamic-acid-rich protein like

NM_003022

0.787 ± 0.13

0.748 ± 0.14

0.594 ± 0.11

EST

AI560951

0.697 ± 0.10

0.655 ± 0.12

0.594 ± 0.10

ATPase, Ca++ transporting, ubiquitous

NM_005173

0.816 ± 0.12

0.777 ± 0.14

0.591 ± 0.12

KIAA0912 protein

AK025247.1

0.843 ± 0.13

0.837 ± 0.17

0.588 ± 0.14

E74-like factor 5 (ets like)

AF115403.1

0.77 ± 0.11

0.748 ± 0.12

0.586 ± 0.11

Tyr 3-/Trp 5-monooxygenase activation protein,?

U28936.1

0.864 ± 0.11

0.965 ± 0.20

0.585 ± 0.16

TGFbeta 1

BC000125.1

0.725 ± 0.10

0.863 ± 0.16

0.583 ± 0.10

Homeo box A6

NM_024014

0.615 ± 0.11

0.712 ± 0.16

0.575 ± 0.13

Agrin

AF016903.1

0.86 ± 0.11

0.87 ± 0.13

0.572 ± 0.12

Chondroitin polymerizing factor

NM_024536

0.837 ± 0.12

1.068 ± 0.15

0.569 ± 0.10

B-cell CLL/lymphoma 6

NM_001706

0.707 ± 0.09

0.739 ± 0.14

0.568 ± 0.10

CCR4-NOT transcription complex, 3

NM_014516

0.803 ± 0.09

1.044 ± 0.22

0.562 ± 0.12

Collagen, type VII, alpha 1

NM_000094

0.786 ± 0.09

0.912 ± 0.13

0.552 ± 0.10

Aldehyde oxidase 1

NM_001159

0.631 ± 0.15

0.664 ± 0.28

0.552 ± 0.12

Solute carrier family 4

NM_003040

1.021 ± 0.10

0.835 ± 0.16

0.551 ± 0.15

Oxidised low density lipoprotein R1

AF035776.1

0.614 ± 0.12

0.76 ± 0.16

0.546 ± 0.15

B-cell CLL/lymphoma 3

NM_005178

0.754 ± 0.17

0.853 ± 0.16

0.532 ± 0.12

TCR gamma variable 9

M13231.1

0.703 ± 0.11

0.569 ± 0.13

0.525 ± 0.11

Actin, gamma 2, smooth muscle

NM_001615

0.946 ± 0.10

0.619 ± 0.13

0.503 ± 0.10

Neurofibromin 1

D12625.1

0.655 ± 0.16

0.576 ± 0.14

0.497 ± 0.17

Keratin 15

NM_002275

0.657 ± 0.10

0.642 ± 0.12

0.486 ± 0.17

SH3-domain GRB2-like endophilin B2

NM_020145

1.109 ± 0.18

0.917 ± 0.16

0.482 ± 0.11

NEL-like 2 (chicken)

NM_006159

0.814 ± 0.09

0.723 ± 0.13

0.451 ± 0.10