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Figure 1 | Molecular Medicine

Figure 1

From: Gene Expression in Temporal Lobe Epilepsy is Consistent with Increased Release of Glutamate by Astrocytes

Figure 1

The comparison of the gene expression patterns in 20 hippocampi from patients with TLE. The dendrogram was obtained by unsupervised hierarchical cluster analysis using Gene Spring software. The analysis included all genes expressed in a microarray analysis using the Affymetrix GeneChip U133A. It shows a primary branching pattern, which separates the sclerotic MTLE (dark green) hippocampi as one cluster. The PTLE (blue) and MaTLE (Red), both being non-sclerotic hippocampi, form a separate group. On the dendrogram, each horizontal color bar denotes the intensity of expression of a particular gene relative to the mean expression value of all samples. The color codes are shown in the color bar where green represents transcript levels below the median and red represents transcript levels above. Yellow is at median. The more intense the color, the greater the level of trust it represents. MTLE = mesial temporal lobe epilepsy; MaTLE = mass associated temporal lobe epilepsy; PTLE = paradoxical temporal lobe epilepsy.

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Molecular Medicine

ISSN: 1528-3658