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Table 2 Neuronal and Glial Counts in Surgically Removed Hippocampi used in this Study

From: Gene Expression in Temporal Lobe Epilepsy is Consistent with Increased Release of Glutamate by Astrocytes

TYPE

Mean % remaining neurons*

Mean Neurons/mm3 in area CA1

Mean Glia/mm3 in area CA1

MTLE

37.8 ±9.6

2974.7 ± 3770

52,670 ± 18,305

MaTLE

81.6 ± 12.8

12,341.2 ± 777.8

15,811 ± 5637

PTLE

84.5 ± 8.5

11,830.7 ± 1566.6

15,814 ± 815.3

  1. *The percentage is the neuronal density across all subregions of the hippocampus in a particular hippocampal type compared with the neuronal density in 20 neurologically normal autopsy controls. The neuron and glial density were estimated from sections adjacent to those used for microarray analysis. In all groups MTLE were significantly different from either MaTLE or PTLE, whereas the latter two groups were not significantly different from each other (Mann Whitney U test, two tail, at P≤ 0.05).
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Molecular Medicine

ISSN: 1528-3658