Figure 5From: Subcellular Localization of APE1/Ref-1 in Human Hepatocellular Carcinoma: Possible Prognostic SignificanceSchematic representation of APE1/Ref-1 stimulation and function. HBV, hepatitis B virus; HCV, hepatitis C virus; HBsAg, hepatitis B virus antigen S; HBx, hepatitis B virus X protein; NS5A, hepatitis C virus nonstructural 5A protein; Rac1, EGR-1, early growth response 1; HIF-1α, hypoxia-inducible factor 1; p53, p53 tumor suppressor protein; AP-1, transcription factor AP1; STAT3, signal transducer and activator of transcription 3.Back to article page