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Table 2 Determinants of sRAGE by stepforward multiple linear regression analysis in diabetic patients

From: Serum Levels of sRAGE, the Soluble Form of Receptor for Advanced Glycation End Products, Are Associated with Inflammatory Markers in Patients with Type 2 Diabetes

Univariate*

Multivariate+

Factors

β

P

β

F

P

Age

−0.045

NS

   

Male sex

0.127

NS

   

BMI

−0.095

NS

   

Waist circumference

−0.015

NS

   

AST

0.208

NS

   

ALT

0.437

0.0001

0.349

2.659

<0.0001

γ-GTP

0.063

NS

   

Total cholesterol

−0.180

NS

   

Triglyceridesa

0.103

NS

   

HDL-cholesterol

−0.200

NS

   

LDL-cholesterol

−0.157

NS

   

Creatinine

0.120

NS

   

Glucosea

−0.054

NS

   

HbA1c

0.006

NS

   

Systolic BP

−0.084

NS

   

Diastolic BP

−0.204

NS

   

Uric acid

0.028

NS

   

MCP-1

0.359

0.001

0.262

0.473

0.007

Adiponectin

0.175

NS

   

TNF-α

0.291

0.006

0.216

67.25

0.023

IL-6

−0.112

NS

   

Hypertension medication

−0.172

NS

   

Hyperlipidemia medication

0.218

0.044

0.074

101.01

0.440

Diabetes medication

−0.002

NS

   

Smoking

−0.027

NS

   

Alcohol use

0.097

NS

   

R 2

0.309

    
  1. β, regression coefficient; *Univariant coefficients; +A stepwise multivariate regression analysis was performed; aLog-transformed values were used; NS, not significant.
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Molecular Medicine

ISSN: 1528-3658