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Table 2 Determinants of sRAGE by stepforward multiple linear regression analysis in diabetic patients

From: Serum Levels of sRAGE, the Soluble Form of Receptor for Advanced Glycation End Products, Are Associated with Inflammatory Markers in Patients with Type 2 Diabetes

Univariate* Multivariate+
Factors β P β F P
Age −0.045 NS    
Male sex 0.127 NS    
BMI −0.095 NS    
Waist circumference −0.015 NS    
AST 0.208 NS    
ALT 0.437 0.0001 0.349 2.659 <0.0001
γ-GTP 0.063 NS    
Total cholesterol −0.180 NS    
Triglyceridesa 0.103 NS    
HDL-cholesterol −0.200 NS    
LDL-cholesterol −0.157 NS    
Creatinine 0.120 NS    
Glucosea −0.054 NS    
HbA1c 0.006 NS    
Systolic BP −0.084 NS    
Diastolic BP −0.204 NS    
Uric acid 0.028 NS    
MCP-1 0.359 0.001 0.262 0.473 0.007
Adiponectin 0.175 NS    
TNF-α 0.291 0.006 0.216 67.25 0.023
IL-6 −0.112 NS    
Hypertension medication −0.172 NS    
Hyperlipidemia medication 0.218 0.044 0.074 101.01 0.440
Diabetes medication −0.002 NS    
Smoking −0.027 NS    
Alcohol use 0.097 NS    
R 2 0.309     
  1. β, regression coefficient; *Univariant coefficients; +A stepwise multivariate regression analysis was performed; aLog-transformed values were used; NS, not significant.